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    November 03

    Yet Another BS Vaccine (This Time GBS) on the Horizon...

    The media love to raise the specter of dead and maimed children as a
    scare tactic to convince the public that more vaccines are necessary.
    The truth about group B strep is that pregnant women are tested in the
    days before giving birth, and if they are found to be GBS-positive,
    given ampicillin during delivery to prevent GBS infection of newborns.
    GBS vaccination is completely unnecessary. Additionally, GBS exists in
    the gut without causing harm, and may actually be useful. It's only
    worrisome when it is present in the birth canal during delivery.
    Eliminating it completely from the body could cause unknown damage.
    Progress in Quest for Group B Strep Vaccine
    Study Shows Vaccine Is Effective in Women of Childbearing Age
    By Charlene Laino
    WebMD Health News
    Reviewed by Louise Chang, MD
    Oct. 30, 2009 (Philadelphia) -- Researchers are a step closer to
    developing a vaccine to protect pregnant women against a serious
    bacterial infection that is a leading cause of death and disability in
    newborns.
    The bug is called group B streptococcus, more commonly referred to as
    group B strep. Pregnant women with group B strep infection or who are
    colonized with the bacteria -- meaning they carry the bug but aren't
    sick from it -- can transmit the bacteria to the fetus during
    delivery. It's commonly found in the vagina and rectum, with about 25%
    of women carrying it at any time; most will carry the bacteria and
    have no symptoms.
    Group B strep can cause life-threatening infections in newborns in the
    hours after birth, during the first week of life, or even several
    months later, says Neil Fishman, MD, an infectious diseases specialist
    at the University of Pennsylvania.
    Currently, women are screened a few weeks prior to delivery; if the
    test is positive, they are given antibiotics to wipe out the
    infection. "But this isn't perfect as the bacteria can be resistant to
    the antibiotics," Fishman tells WebMD.
    Developing a vaccine against group B strep is a major goal, he says.
    The new study involved 650 women of childbearing age who were not
    carriers of group B strep. About half were given the new vaccine. The
    women were checked for group B strep bacteria twice a month for 18
    months.
    The vaccine caused a modest but lasting reduction in group B strep
    colonization in the vagina and rectum, says researcher Sharon Hillier,
    PhD, of the Magee-Womens Research Institute at the University of
    Pittsburgh. Colonization of the genital or gastrointestinal tract is
    the major risk factor for infections.
    The vaccine also elicited a strong immune response against the
    bacteria, she tells WebMD. And the vaccine was safe.
    Emory University's Larry Pickering, MD, a senior advisor to the CDC's
    National Immunization Program, says that while preliminary, the work
    is very encouraging.
    "It's important in that they showed it prevented colonization" in both
    the GI tract and vagina, he tells WebMD. "But there's still a lot of
    work to do."

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